Dopaminergic antagonists for alcohol dependence
نویسندگان
چکیده
منابع مشابه
Opioid antagonists in the treatment of alcohol dependence.
This article reviews the use of opioid antagonists in the pharmacologic treatment of alcohol dependence. The rationale for using the opioid antagonists naltrexone and nalmefene to prevent relapse in alcohol-dependent subjects is discussed by reviewing past and current clinical trials. The role of psychotherapies, particularly coping skills therapy, in combination with opioid antagonists is high...
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Alcoholism is a major public health problem that is detrimental to the affected individuals as well as to society as a whole. It has been popular belief that alcohol dependence can be controlled through will power, skill building, and support. Therefore, psychosocial therapies have historically been the most utilized treatments for alcohol use disorders.(1).
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A lcohol is one of the oldest and most widely used and abused of all psychoactive drugs. Although alcohol ingestion impacts most organ systems, its effects on the brain are of considerable interest, given alcohol’s many neuropharmacological actions, including its intoxicating, sedative, anxiolytic, reinforcing, and addictive properties (1). However, elucidating the cellular and molecular target...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2018
ISSN: 1465-1858
DOI: 10.1002/14651858.cd008460.pub2